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I've seen it used in a couple of very specific situations: valuing O&G exploration companies (where you are drilling a series of prospects with a rough idea of % chance of success on each and the probabiltiy distribution, plus there is some path dependency) or early stage pharma (similar).

For most companies - what would the point be? You're trying to value a company based on fundamentals, unless you're going to start putting together probability distributions for what the revenue line looks like (which would be garbage in / garbage out) there's nothing to 'simulate'.

 

If you have a very good idea of the % chance of success of each drug in a company's development pipeline at each stage of approval, and there are a few different drugs in the pipeline, then yeah running a Monte Carlo simulation could make some sense. 

I'm not a pharma investor but I'd be amazed if you ever have enough information on the probabilities to make Monte Carlo anything other than garbage in / garbage out.

 

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