2048 Ventures is a thesis-driven venture capital firm headquartered in New York, United States. Founded in 2018 by Alex Iskold, the firm focuses on leading pre-seed and seed-stage investments in North America, with a particular emphasis on Vertical AI, deep technology, health, and biotech startups.

The fund positions itself as a “first check in” investor, backing technical founders who are building transformative companies at the earliest stages. With a hands-on approach, 2048 Ventures provides both capital and operational support, aiming to be the lead institutional investor in its portfolio companies’ first rounds.

Since inception, the firm has built a portfolio spanning multiple industries and geographies, reflecting its conviction-driven model and sector-specific theses. Its team combines venture experience with entrepreneurial backgrounds, enabling it to work closely with founders in shaping strategy, recruiting talent, and scaling early operations.